- A team of South Korean scientists developed a possible cure for baldness
- The team developed a biochemical substance that induces hair follicle regeneration
- Current hair loss treatments are limited to slowing hair loss or accelerating hair growth
South Korean scientists led by Professor Choi Kang-yeol of Yonsei University developed a biochemical substance that stimulates new hair growth.
Unlike current hair loss treatments which have been limited to slowing hair loss or accelerating hair growth, the newly developed substance induces hair follicle regeneration.
The team discovered a protein called “CXXC-type zinc finger protein 5” that binds to Dishevelled protein. The binding of these proteins interrupts with hair follicle development and regeneration.
Based on this finding, the scientists developed a biochemical substance called called “PTD-DBM” that prevents the CXXC protein from interacting with the Dishevelled protein.
“We have found a protein that controls the hair growth and developed a new substance that promotes hair regeneration by controlling the function of the protein. We expect that the newly developed substance will contribute to the development of a drug that not only treats hair loss but also regenerates damaged skin tissues,” Professor Kang-yeol said.
When tested on laboratory mice over a 28-day period, the substance promoted the growth of hair follicles. Hair was also found to grow at a faster rate when applied to mice along with a chemical called valproic acid.
The findings of Professor Choi Kang-yeol’s team were published in the Journal of Investigative Dermatology.